Ah, I see. So it could be less severe for both vaccinated and unvaccinated, but have a slightly higher degree of vaccine escape against Omicron than Delta could give you the graph as shown?
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Tomorrow we will be a statistic.
DS tested positive for covid this morning 
He has a slight cough and woke up flushed. He said he didnât sleep well and he has gone back to sleep this morning. Hoping we get through it all healthily 
WTAF is this chart about though?? 103k cases yesterday?? Thatâs more than England 
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Sorry to hear about ds. Hope the rest of you make it through unscathed.
I find that chart isnât always accurate compared to my state reporting site. It could be they got a data dump that day from some late reporting sites and so it shows a spike that day.
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Itâs so odd thatâs the are no accompanying headlines about it.
There have been several days lately where the reported numbers are â0â which obviously isnât right, but even if you add all of those up as having been reported at once (assuming the daily average) it wouldnât give 100k!!
No idea what itâs all about.
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Hmmmm. Maybe they found some earlier unreported data and threw it in there. I know NC does that every few months it seems so some of our spikes are really data that wasnât reported in the previous few weeks. Do you have a local source you can check the data on?
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I always just use the Google data, but Iâll have a checkâŚ
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So the gov.scot link says that the figures for the 11th were only 7k. Something definitely not right with the Google figures then.
My use of only is terrifying 
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IKR?
âOnly 200k deaths/yearâ sounds pretty brilliant right now considering thatâs how many the US has had in the last 4 months. 
SoâŚyâknowâŚjust 4x flu and pneumonia put together.
Iâm seeing more and more trustworthy people saying with the transmissibility and immune evasiveness of BA.1, let alone whatever BA.2 comes in at, herd immunity isnât even a viable concept anymore. Thatâs why 200k. 
And that isnât even among the scarier theories Iâm seeing floated as possibilities.
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CNBC reporting that Pfizer pulled back its application for the under 5s. This is a gut punch.
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CNN has an article that itâs the USFDA who is postponing the 2/15 meeting.
âThis will give the agency time to consider the additional data, allowing for a transparent public discussion as part of our usual scientific and regulatory processes for COVID-19 vaccines. We will provide an update on timing for the advisory committee meeting once we receive additional data on a third dose in this age group from the companyâs ongoing clinical trial and have an opportunity to complete an updated evaluation,â acting FDA Commissioner Dr. Janet Woodcock and Dr. Peter Marks, director of the FDAâs Center for Biologics Evaluation and Research, said in a statement."
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Canât heart this. Reeling from the gut punch now too. I was surprised that they scheduled the meeting so quickly, but it seemed like things were aligning so that they could work quickly and now, they realize they canât work quite that quick.
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Ugh. Iâm so, so sorry for you and all the impacted families.
âThe companies expect to have three-dose protection data available in early April.â
YLE:
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Here is the FDA statement:
âGiven the recent omicron surge and the notable increase in hospitalizations in the youngest children to their highest levels during the pandemic so far, we felt it was our responsibility as a public health agency to act with urgency and consider all available options, including requesting that the company provide us with initial data on two doses from its ongoing study. The goal was to understand if two doses would provide sufficient protection to move forward with authorizing the use of the vaccine in this age group. Our approach has always been to conduct a regulatory review thatâs responsive to the urgent public health needs created by the pandemic, while adhering to our rigorous standards for safety and effectiveness. Being able to begin evaluating initial data has been useful in our review of these vaccines, but at this time, we believe additional information regarding the ongoing evaluation of a third dose should be considered.â
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Follow up to above post. Concerns about expectation setting by using terms like âpan-coronavirus vaccinesâ when itâs really just a subset of the coronaviruses.
^ Deeply credentialled
https://twitter.com/florian_krammer/status/1492124831713841154?s=21
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That is my lay personâs interpretation of the graph.
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Thanks for linking to these statements. Itâs not entirely surprising, but it was really starting to sound real when our local health department director updated that she had a timeline to receive the doses, so itâs hard to pull back. Especially when the FDAâs statement includes:
In the meantime, the best way to protect children, including when they are at school or daycare, is to practice social distancing and masking in accordance with public health recommendations, and for their family members and caregivers to get vaccinated or receive a booster dose when eligible.
At least where I am, thereâs not one public or charter school that can enforce them and no private one within a reasonable driving distance that will even take a measure of those precautions. So it puts the nail in the coffin on any in-person preschool experience for DS4. We had hoped that he would be able to start sometime this later half of the year, but if his 5th birthday comes before an <5 approval, it will be Memorial Day (and only a week or two left of the school) before he can be protected enough for us to feel comfortable with him in a school. We do have a case threshold weâre willing to accept (CDCâs Low) sending him to school with a partial or no vaccination, but I donât think weâve ever even come close to CDCâs Moderate level since we saw our first real wave of cases in Summer 2020. So even if it may be possible now, it feels like a far-off fantasy dream world.
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Ok, hereâs something related of interest. Baylor College of Medicine is actually part of the trial. (see note at bottom of slide)
The relevant part of the update starts at the 10:30 mark, but the really interesting comment is at the 11:25 mark.
He mentions enrolling more 2-5s at a âhigher doseâ. I hadnât heard this, but it entirely would make sense that, in to adding a 3rd dose approach to the original trial, they might have run a separate parallel trial with 2 higher doses? Maybe that data is coming back stronger than the 3 dose approach, with that being the new data that has them putting the brakes back on until they get all the data squared away? Waiting a bit longer for only 2 doses 3 weeks apart to get fully vaxxed might not be that much longer than starting a 3 dose regime that would occur over almost 3 months?
Video:
This shows the 3rd dose was the same as the first 2:
The other interesting bit from the update is this. It was done in the UK. I donât think US ethics rules would allow this?
An expert (maybe Your Local Epidemiologist?) I read said back in December suggested that it would make sense for Pfizer to start a new trial with 2 larger doses in addition to the 3rd smaller dose so that Pfizer wouldnât lose time if the 3rd smaller dose didnât work. I listened to the video and I am confused as to whether Pfizer is starting this now or started it back in December. It would be very upsetting if the new trial is being started now (2 months later) instead of back in December.
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From what I was reading, they havenât maxed out the multi year study on under 5s yet, so they have been enrolling throughout the last several months. They had higher doses listed as potentials in the study materials so my guess is theyâve been doing those ever since the lower dose data came in less than they wanted.
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