A lot depends on how much vaccine is available and how many people get the vaccine. We should know more about that in the spring. I know a number of people in my area who work in hospitals and have been vaccinated already and only 1 who declined (she wants to see what happens over the next couple months). Most of my friends say they will get the vaccine as soon as it is available to them. I suspect, however, that in some areas of the country, people are more skeptical of the vaccine than my area.
Of course, there is also the terrible scenario where one of these mutations proves resistant to the vaccine (I sure hope not).