Is that Columbus Day weekend? Regardless, crowds in October can be surprisingly large due to the fervor over the Halloween season, which has become one of the most popular times of year for locals and visitors alike to spend time at DLR.
That said, it’s nothing like Christmas or New Years or other major holidays, and at least the temperatures are nice. Some days are still relatively empty, especially weekdays in the morning and early afternoon. If it’s a Halloween party day, the parks will likely get busy in the early evening when the ticketed event participants are allowed to enter (plus a lot of them are season pass holders so they can go to both parks and don’t have to wait till the event starts to be let in).
I would have a touring plan ready but keep your fingers crossed that your days won’t be too busy.